July 10, 2025
Education News Canada

UNIVERSITY OF CALGARY
UCalgary research aims to expand non-surgical castration in Canadian livestock

July 10, 2025

Dr. Maria Camilla Ceballos, associate professor of animal welfare and behaviour at the University of Calgary Faculty of Veterinary Medicine (UCVM), is working to improve the welfare of livestock across Canada and around the world. 

Ceballos, PhD, leads a team exploring immuno-castration, an alternative to the traditional, often painful, castration of livestock. Already embraced by many countries worldwide, this method not only promises to elevate animal welfare, but also brings economic advantages to producers and consumers.

The initiative is funded by Open Philanthropy,  a global supporter of scientific research in high-impact areas such as finding new ways to help farm animals.

Understanding immuno-castration

Immuno-castration is a pharmaceutical innovation that triggers the production of antibodies that work against reproductive hormones, effectively halting puberty in animals. This approach curbs aggression, eases housing and handling, and prevents unwanted mating, particularly beneficial in male livestock. 

For pigs, it also eliminates "boar-taint," an accumulation of hormones that can lead to unpleasant odours and flavours in meat from post-pubescent pigs. 

Unlike traditional castration methods, which involve painful removal of testicles while animals are conscious, immuno-castration requires just two injections and causes no tissue damage. 

Method has global appeal

This vaccine is commercially available and approved for use in pigs in more than 60 countries, and has been used in Canada since 2012. In some countries, it is also available for cattle, but its use depends on local regulatory approval. 

The method is also being explored for use in:

  • sheep
  • goats
  • horses
  • wildlife 

Countries such as Colombia and Brazil have successfully integrated immuno-castration in their pig production systems, with adoption rates at an impressive 90 per cent and 84 per cent, respectively. 

Ceballos emphasizes the significance of learning from these global leaders. "Understanding the drivers, benefits, and challenges behind the widespread adoption of immuno-castration in these countries, and how they successfully implemented it, can provide valuable insights to inspire behavioural changes in nations where its use remains limited, ultimately benefiting the entire pig value chain," she says. 

The Canadian context


Maria Ceballos. Photo Credit: UCVM

In Canada, immuno-castration is used in about 25 per cent of the produced male pigs, with higher adoption rates among female pigs. Ceballos is determined to uncover factors driving its use and identify any obstacles hindering broader adoption within the Canadian swine industry. 

Ceballos' team includes:

  • Dr. Maria Hotzel, professor in animal science and rural development at the Federal University of Santa Catarina, Brazil
  • Dr. Beth Ventura, animal welfare scientist at the University of Lincoln in the U.K.
  • Dr. Guillaume Lhermie, director of the Simpson Centre for Food and Agricultural Policy, and professor in the Faculty of Veterinary Medicine at UCalgary
  • Victor Brusin, master's student in animal behaviour and welfare, UCalgary.

"Our research aims to pinpoint who is using it, what motivates them, and the challenges they face, so we can identify bottlenecks preventing its wider implementation," Ceballos explains. 

Benefits for all

The advantages of immuno-castration extend across the entire production chain. Animals benefit from reduced pain, risk of infections and diseases associated with surgical procedures, leading to significantly improved welfare. Producers see gains in growth efficiency and feed utilization in immuno-castrated males, while consumers enjoy higher quality meat; leaner, juicier, and more tender. 

Furthermore, this method promotes sustainability, with a carbon footprint reduction of up to 3.6 per cent compared to traditional practices. 

Research looks at animal welfare

In today's world, animal welfare has become a pivotal factor in consumer choices, and UCVM is at the forefront of addressing this critical concern. Immuno-castration represents a superior alternative, a technology poised for broader development and adoption. 

It offers a compassionate solution that enhances the welfare of livestock while delivering economic and quality benefits throughout the production chain. 

Through initiatives like Ceballos' research, UCalgary is setting the stage for change in the swine industry and beyond. By integrating scientific advancements with practical, economically viable solutions, the university is leading the way in creating a more sustainable and humane future for Canadian livestock production. 

For more information

University of Calgary
2500 University Drive N.W.
Calgary Alberta
Canada T2N 1N4
www.ucalgary.ca/


From the same organization :
261 Press releases